Increase in exhaled nitric oxide and protective role of the nitric oxide system in experimental pulmonary embolism
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منابع مشابه
Increase in exhaled nitric oxide and protective role of the nitric oxide system in experimental pulmonary embolism.
BACKGROUND AND PURPOSE Pulmonary embolism (PE) represents a real diagnostic challenge. PE is associated with pulmonary hypertension due to pulmonary vascular obstruction and vasoconstriction. We recently reported that pulmonary gas embolism transiently increases exhaled nitric oxide (FENO), but it is not known whether solid emboli may alter FENO, and whether an intact endogenous NO synthesis ha...
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Nitric oxide (NO) is an important modulator of the pulmonary circulation both at basal state and in pulmonary hypertension. Low levels of NO are detectable in exhaled gas which is believed to mirror pulmonary NO formation and elimination. Pulmonary embolism is a disease characterised by pulmonary hypertension, and thereby increased afterload of the right ventricle, and by disturbed gas exchange...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 2007
ISSN: 0007-1188
DOI: 10.1038/sj.bjp.0707001